gb88Suen JY, et al. Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110). Br J Pharmacol. 2012 Mar;165(5):1413-23. [Content Brief]An important finding has been reported that GB88 inhibits the PAR2 activated Ca 2+ release, induced by trypsin or synthetic peptide in vitro (28). The GB88