Phase separation of Nur77 mediates celastrol-induced mitophagy

nuri77Nuclear receptor subfamily 4 group A member 1 (NR4A1; also termed Nur77TR3NGFIB), a member of the nuclear receptor superfamily, is expressed as an early response gene toFure 1 Loss of Nur77 in BMDMs leads to enhanced efferocytosis due to an increased integrin β3 and β5 snaling.(A) In vitro uptake of fluorescently-labeled apoptotic